Publications

The following manuscripts have been published or are currently in press. Listings are in chronological order, unless otherwise noted.

Research Publication 2
Title Publication Date/Location
Post-Traumatic Stress Disorder Predicts Future Weight Change in the Millennium Cohort Study Obesity 2015 Apr;23(4):886-92

LeardMann CA, Woodall KA, Littman AJ, Jacobson IG, Boyko EJ, Smith B, Wells TS, Crum-Cianflone NF

Data from Millennium Cohort Study participants (2001-2008), consisting of US Service members and Veterans, were used to prospectively examine the association between posttraumatic stress disorder (PTSD) and weight change. A significant and consistent association of PTSD with subsequent three-year weight gain and the development of obesity was found in adjusted models. Given these findings, weight gain and development of obesity should be considered important comorbidities for PTSD; existing screening and treatment programs should make sure to address these associated conditions.

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Postcards Encourage Participant Updates Epidemiology 2009 Mar;20(2):313-4

Welch KE, LeardMann CA, Jacobson IG, Speigle SJ, Smith B, Smith TC, Ryan MAK, for the Millennium Cohort Study Team

The results of this study quantify and confirm that semiannual appreciatory contact is an effective way to maintain communication with a highly mobile participant population while prompting updates of contact information.

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Posttraumatic Stress Disorder and Depression Among US Military Health Care Professionals Deployed in Support of the Operations in Iraq and Afghanistan Journal of Traumatic Stress 2012 Dec;25(6):616-23

Jacobson IG, Horton JL, LeardMann CA, Ryan MAK, Boyko EJ, Wells TS, Smith B, Smith TC, for the Millennium Cohort Study Team

Among military personnel deployed with combat experience, health care professionals did not have increased odds for new-onset PTSD or depression over time compared to individuals in other occupations. Combat experience significantly increased the odds for new-onset PTSD or depression among deployed health care professionals, suggesting that combat experience, not features specific to being a health care professional, was the key exposure explaining development of these outcomes.

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Posttraumatic Stress Disorder Symptom Association With Subsequent Risky and Problem Drinking Initiation Journal of Addiction Medicine 2018 Sep/Oct;12(5):353-362

Bensley KM, Seelig AD, Armenta RF, Rivera AC, Peterson AV, Jacobson IG, Littman AJ, Maynard C, Bricker JB, Boyko EJ, Rull RP, and Williams EC

This study investigated the association between PTSD symptoms and symptom clusters and the initiation of risky and problem drinking. One PTSD symptom (irritability/anger) was associated with a higher risk of risky drinking initiation. Five PTSD symptoms (restricted affect, sense of foreshortened future, exaggerated startle response, sleep disturbance, and irritability/anger) and two symptom clusters (dysphoric arousal and emotional numbing) were associated with an increased risk of problem drinking initiation.

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Predeployment Sleep Duration and Insomnia Symptoms as Risk Factors for New-Onset Mental Health Disorders Following Military Deployment Sleep 2013 Jul 1;36(7):1009-1018

Gehrman P, Seelig AD, Jacobson IG, Boyko EJ, Hooper TI, Gackstetter GD, Ulmer CS, Smith TC

This study showed that combat-related trauma and predeployment insomnia symptoms were significantly associated with developing posttraumatic stress disorder, depression, and anxiety following deployment. Assessment of insomnia symptoms predeployment may help to better identify those at highest risk for subsequent adverse mental health outcomes.

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Preinjury Psychiatric Status, Injury Severity, and Postdeployment Posttraumatic Stress Disorder Archives of General Psychiatry 2011 May;68(5):496-504

Sandweiss DA, Slymen DJ, LeardMann CA, Smith B, White MR, Boyko EJ, Hooper TI, Gackstetter GD, Amoroso PJ, Smith TC, for the Millennium Cohort Study Team

Physical injuries were significantly associated with postdeployment PTSD. Baseline psychiatric status was also significantly associated with postdeployment PTSD, irrespective of injury severity. Deployed service members who suffer from a predeployment psychiatric condition or injury while deployed may benefit from interventions targeted to prevent postdeployment PTSD or ensure early identification and treatment.

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Prescription Stimulants and Post-Traumatic Stress Disorder Among US Military Service Members Journal of Traumatic Stress 2015 Dec;28(6):585-589

Crum-Cianflone NF, Frasco M, Armenta RF, Phillips CJ, Horton J, Ryan MAK, Russell DW, LeardMann CA

Millennium Cohort data from U.S. military members who completed the baseline survey, and two follow-up surveys were evaluated to determine associations between receipt of prescription stimulants and PTSD. Prescription stimulants were significantly associated with incident PTSD after adjustment for attention-deficit/hyperactivity disorder, baseline mental and physical health status, deployment experiences, and other known confounders. Findings from this study may inform the underlying pathogenesis of and preventive strategies for PTSD.

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Prior Assault and Posttraumatic Stress Disorder After Combat Deployment Epidemiology 2008 May;19(3):505-12

Smith TC, Wingard DL, Ryan MAK, Kritz-Silverstein D, Slymen DJ, Sallis JF, for the Millennium Cohort Study Team

In contrast to hypotheses that survival from trauma represents or confers resilience, these findings suggest vulnerability to combat stress and PTSD among survivors of prior assault.

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Prior Health Care Utilization as a Determinant to Enrollment in a 21-Year Prospective Study, the Millennium Cohort Study European Journal of Epidemiology 2008 Feb;23(2):79-87

Wells TS, Jacobson IG, Smith TC, Spooner CN, Smith B, Reed RJ, Amoroso PJ, Ryan MAK, for the Millennium Cohort Study Team

Few health differences between Millennium Cohort responders and non-responders were found when comparing healthcare utilization in the 12 months preceding study invitation.

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Profile of Two Cohorts: UK and US Prospective Studies of Military Health International Journal of Epidemiology 2012 Oct;41(5):1272-82

Pinder RJ, Greenberg N, Boyko EJ, Gackstetter GD, Hooper TI, Murphy D, Ryan MA, Smith B, Smith TC, Wells TS, Wessely S, for the Millennium Cohort Study Team

Despite differences and limitations in methodologies, analyses of these two cohorts provide the prospect of driving improvement and innovation in military health and extending findings to other occupational populations.

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