Publications

The following manuscripts have been published or are currently in press. Listings are in chronological order, unless otherwise noted.

Research Publication 2
Title Publication Date/Location
Association of Combat Experiences With Suicide Attempts Among Active-Duty US Service Members JAMA Network Open 2021;4(2):e2036065

LeardMann CA, Matsuno R, Boyko EJ, Powell TM, Reger MA, Hoge CW, for the Millennium Cohort Study Team

Among 57,841 active-duty service members who had deployed, high combat severity and certain specific combat experiences were associated with suicide attempts. However, these associations were mostly accounted for by mental disorders, especially PTSD. Findings suggest that service members who experience high levels of combat or are exposed to certain types of combat experiences, involving unexpected events or those that challenge moral or ethical norms, may have an increased risk of a suicide attempt, either directly or indirectly through mental disorders.

View full text

Assessing Nonresponse Bias at Follow-Up in a Large Prospective Cohort of Relatively Young and Mobile Military Service Members BMC Medical Research Methodology 2010 Oct;10(1):99

Littman AJ, Boyko EJ, Jacobson IG, Horton JL, Gackstetter GD, Smith B, Hooper TI, Amoroso PJ, Smith TC, for the Millennium Cohort Study Team

In this study population, nonresponse to the follow-up questionnaire did not result in appreciable bias as reflected by comparing measures of association for selected outcomes using complete case and inverse probability weighted methods.

View full text

Application of Latent Semantic Analysis for Open-Ended Responses in a Large, Epidemiologic Study BMC Medical Research Methodology 2011 Oct;11:136

Leleu TD, Jacobson IG, LeardMann CA, Smith B, Foltz PW, Amoroso PJ, Derr M, Ryan MAK, Smith TC, for the Millennium Cohort Study Team

Using latent semantic analysis to analyze the final open-ended text field on the Millennium Cohort questionnaire helped identify important topic areas for future survey questions and also revealed the most common areas of concern for participants were illness and injuries, exposures, and exercise. Subjects with worse self-reported general health were more likely to provide a response in the open-ended text field than subjects with better general health.

View full text

Anthrax Vaccination in the Millennium Cohort: Validation and Measures of Health American Journal of Preventive Medicine 2007 Apr;32(4):347-53

Smith B, Leard CA, Smith TC, Reed RJ, Ryan MAK, for the Millennium Cohort Study Team

The largest ever evaluation of this topic revealed strong validity of self-reported vaccination, as well as unique health features of the small subset who may misreport vaccination. This work won awards at two research conferences in 2006.

View abstract

All-Cause Mortality Among United States Military Personnel: Findings From the Millennium Cohort Study Annals of Epidemiology 2024 Aug 28 | doi: 10.1016/j.annepidem.2024.08.006 | Online ahead of print

Carey FR, Harbertson J, Sharifian N, Boyko EJ, Rull RP

Previous history of deployment, female sex, and Hispanic ethnicity were protective for mortality, while combat exposure, enlisted rank, being in the Army, and health factors (e.g., stressful life events, smoking, alcohol use) were risk factors for mortality among OEF/OIF/OND service members and veterans over a 20 year period.

View full text

Alcohol Use and Alcohol-Related Problems Before and After Military Combat Deployment Journal of the American Medical Association 2008 Aug;300(6):663-75

Jacobson IG, Ryan MAK, Hooper TI, Smith TC, Amoroso PJ, Boyko EJ, Gackstetter GD, Wells TS, Bell NS, for the Millennium Cohort Study Team

Findings suggest that Reserve and National Guard personnel and younger service members who deploy with reported combat exposures are at increased risk of new-onset heavy weekly drinking, binge drinking, and other alcohol-related problems.

View full text

A temporal analysis of mental health symptoms relative to separation from the military Depression and Anxiety 2022 Apr;39(4):334- 343

Porter B, Carey FR, Roenfeldt KA, Rull RP, Castro CA

This paper examined mental health symptoms among 23,887 active duty Millennium Cohort Study participants who completed a survey within one year of their separation from the military. While significant, timing prior to or after separation did not have a practical impact on mental health among all study participants, accounting for less than 0.2% of variance in mental health symptoms. However, among participants with Other Than Honorable or General discharges, timing to separation accounted for 5.1% and 3.6% of the variance in posttraumatic stress disorder and depression symptoms, respectively; mental health symptoms increased among these participants around the time of separation and remained elevated in the period following separation. Increased outreach at the time of separation and post-separation is needed for service members with bad paper discharges.

View abstract

A Prospective Study of Lupus and Rheumatoid Arthritis in Relation to Deployment in Support of Iraq and Afghanistan: the Millennium Cohort Study Autoimmune Diseases 2011 Nov;741267

Jones KA, Granado NS, Smith B, Slymen DJ, Ryan MAK, Boyko EJ, Gackstetter GD, Phillips CJ, Smith TC, for the Millennium Cohort Study Team

Newly reported lupus was not associated with military deployment in support of the current operations in Iraq and Afghanistan when compared with nondeployers. Our study did note a significantly decreased risk of newly reported rheumatoid arthritis among deployers with and without combat exposures when compared with nondeployers; the reason for this finding is unknown, but may be due to a selection effect for deployment.

View full text

A Prospective Study of Depression Following Combat Deployment in Support of the Wars in Iraq and Afghanistan American Journal of Public Health 2010 Jan;100(1):90-9

Wells TS, LeardMann CA, Fortuna SO, Smith B, Smith TC, Ryan MAK, Boyko EJ, Blazer D, for the Millennium Cohort Study Team

Findings emphasize that exposure to combat, rather than deployment itself, among men and women significantly increase the risk of new-onset depression.

View abstract

A Longitudinal Investigation of Smoking Initiation and Relapse Among Younger and Older US Military Personnel American Journal of Public Health 2015 Jun;105(6):1220-1229

Boyko EJ, Trone DW, Peterson AV, Jacobson IG, Littman AJ, Maynard C, Seelig AD, Crum-Cianflone NF, Bricker JB

Smoking initiation and relapse were examined among current and former military Service members. Deployment with combat experience predicted higher initiation and relapse rates. Additionally, depending on the panel, prior mental health disorders, life stressors, and other military and nonmilitary characteristics independently predicted initiation and relapse.

View abstract

The appearance of hyperlinks does not constitute endorsement by the Department of Defense of non-U.S. Government sites or the information, products, or services contained therein. Although the Department of Defense may or may not use these sites as additional distribution channels for Department of Defense information, it does not exercise editorial control over all of the information that you may find at these locations. Such links are provided consistent with the stated purpose of this website.

Publication badge scores are provided by Altmetric.