The following manuscripts have been published or are currently in press. Listings are in chronological order, unless otherwise noted.

Title | Publication | Date/Location |
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Newly Reported Hypertension After Military Combat Deployment in a Large Population-Based Study | Hypertension | 2009 Nov;54(5):966-73 |
Granado NS, Smith TC, Swanson GM, Harris RB, Shahar E, Smith B, Boyko EJ, Wells TS, Ryan MAK, for the Millennium Cohort Study Team Findings suggest that deployers who report multiple combat exposures, especially those who personally witnessed a death due to war or disaster, are at higher risk for newly-reported hypertension, possibly indicating a stress-induced hypertensive effect. |
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Newly Reported Lupus and Rheumatoid Arthritis in Relation to Deployment Within Proximity to a Documented Open-Air Burn Pit in Iraq | Journal of Occupational and Environmental Medicine | 2012 June;54(6):698-707 |
Jones KA, Smith B, Granado NS, Boyko EJ, Gackstetter GD, Ryan MAK, Phillips CJ, Smith TC, for the Millennium Cohort Study Team This study examined the incidence lupus and rheumatoid arthritis in relation to Army and Air Force personnel deployed within a 3- and 5-mile radius of documented open-air burn pits located in Iraq at Joint Base Balad, Camp Speicher, and Camp Taji. Overall, the results indicate no elevated risk of newly reported lupus or rheumatoid arthritis in the combined three-camp analysis. However, possible exposure at Balad was individually associated with newly reported lupus, although only two cases were at this site. Additional studies, including individual exposure data, are needed to further investigate these associations. |
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Newly Reported Respiratory Symptoms and Conditions Among Military Personnel Deployed to Iraq and Afghanistan: A Prospective Population-Based Study | American Journal of Epidemiology | 2009 Dec;170(11):1433-42 |
Smith B, Wong CA, Smith TC, Boyko EJ, Gackstetter GD, Ryan MAK, for the Millennium Cohort Study Team Elevated risk for self-reported respiratory symptoms was found among Army and Marine Corps personnel deployed in support of operations in Iraq and Afghanistan. No increased risk for self-reported asthma, bronchitis, or emphysema was found. |
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Obesity and Associated Adverse Health Outcomes Among US Military Members: Findings from the Millennium Cohort Study | Obesity | 2016 Jul;24(7):1582-1589 |
Rush T, LeardMann CA, Crum-Cianflone NF This study examined body weight among Service members and Veterans over time (2001-2007), finding a doubling of the prevalence of obesity. Obesity rates were significantly higher among veterans, including among those recently discharged from service. The study found that military personnel, even during service time, experienced weight gain and the development of obesity. Individuals with obesity had higher rates of adverse physical, mental, and functional health, suggesting that weight control should be a DoD and national priority. |
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Occupation and Risk of Traumatic Brain Injury in the Millennium Cohort Study | Military Medicine | 2022 Feb 27;usac035 |
Jannace KC, Pompeii L, Gimeno Ruiz de Porras D, Perkison WB, Yamal JM, Trone DW, Rull RP Using 2014-16 survey data from active duty 33,646 Millennium Cohort Study participants, we assessed the association between their primary military occupational categories (MOC) and self-reported traumatic brain injury (TBI) sustained during military service. Adjusting for military and demographic characteristics and pre-service TBI, all MOCs except for health care MOCs were statistically significantly more likely to experience service-related TBI compared with “Administration & Executive” MOCs, while those in “Infantry/Tactical Operations” had the highest odds of service-related TBI. Enlisted (28%) personnel were more likely than officers (24%) to experience a service-related TBI. Results highlight the importance of targeting specific occupational categories for TBI risk reduction and a quantification of risk among enlisted MOCs suggests a need for further research into the causes of TBI. |
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Patterns of Smoking and Unhealthy Alcohol Use Following Sexual Trauma Among US Service Members | Journal of Traumatic Stress | 2017 Oct;30(5):502-511 |
Seelig AD, Rivera AC, Powell TM, Williams EC, Peterson AV, Littman AJ, Maynard C, Street AE, Bricker JB, Boyko EJ Following sexual assault while serving in the military, women had double the risk for unhealthy alcohol use relapse while men had 6 times the risk for smoking relapse compared with women and men who did not experience sexual assault, respectively. No other associations between sexual trauma (assault or harassment) and subsequent smoking or unhealthy alcohol use were observed. Substance use prevention measures are recommended for those who experience sexual assault and have a history of smoking and unhealthy alcohol use. |
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Post-Traumatic Stress Disorder Predicts Future Weight Change in the Millennium Cohort Study | Obesity | 2015 Apr;23(4):886-92 |
LeardMann CA, Woodall KA, Littman AJ, Jacobson IG, Boyko EJ, Smith B, Wells TS, Crum-Cianflone NF Data from Millennium Cohort Study participants (2001-2008), consisting of US Service members and Veterans, were used to prospectively examine the association between posttraumatic stress disorder (PTSD) and weight change. A significant and consistent association of PTSD with subsequent three-year weight gain and the development of obesity was found in adjusted models. Given these findings, weight gain and development of obesity should be considered important comorbidities for PTSD; existing screening and treatment programs should make sure to address these associated conditions. |
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Postcards Encourage Participant Updates | Epidemiology | 2009 Mar;20(2):313-4 |
Welch KE, LeardMann CA, Jacobson IG, Speigle SJ, Smith B, Smith TC, Ryan MAK, for the Millennium Cohort Study Team The results of this study quantify and confirm that semiannual appreciatory contact is an effective way to maintain communication with a highly mobile participant population while prompting updates of contact information. |
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Posttraumatic Stress Disorder and Depression Among US Military Health Care Professionals Deployed in Support of the Operations in Iraq and Afghanistan | Journal of Traumatic Stress | 2012 Dec;25(6):616-23 |
Jacobson IG, Horton JL, LeardMann CA, Ryan MAK, Boyko EJ, Wells TS, Smith B, Smith TC, for the Millennium Cohort Study Team Among military personnel deployed with combat experience, health care professionals did not have increased odds for new-onset PTSD or depression over time compared to individuals in other occupations. Combat experience significantly increased the odds for new-onset PTSD or depression among deployed health care professionals, suggesting that combat experience, not features specific to being a health care professional, was the key exposure explaining development of these outcomes. |
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Posttraumatic Stress Disorder and Risk of Selected Autoimmune Diseases among US Military Personnel | BMC Psychiatry | 2020 Jan 15; 20 (1):23 |
Bookwalter DB, Roenfeldt KA, LeardMann CA, Kong SY, Riddle MS,Rull RP This study investigated the association between PTSD and risk of developing selected autoimmune diseases among US active duty service members. Among 120,572 participants followed for an average of 5 years, risk of any of the selected new-onset autoimmune diseases was 58% higher for those with a history of PTSD compared to those with no history. Observed associations did not differ by specific types of trauma experienced. Future research is needed to understand the physiological pathways that may link PTSD with increased risk of immune-mediated inflammatory diseases. |
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